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ABOUT ME

Name              : Siva Ramakrishna Uppalapati

AKA               : Siva Ram

Qualification   : PhD in Microbiology

Father              : Jagan Mohan U

Mother            : Krishna Veni U

DOB                : 20th July, 1985

Nationality      : Indian

Medium of Education   : English

Languages       : English, Telugu & Hindi       

 

 

 

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Health           : Non-smoker, Non-alcoholic

Blood group  : O +ve

Race:             : Asian

Veteran         : No

Disability      : None

Hobbies        : Medical fiction & Sci-fi novels

Games          :  Table tennis & Cricket

Faith             : Raised as Hindu but believes in

                        Unity of Faith

 

 

 

I am interested in development of novel antibiotics/immunotherapeutics/vaccines against multiple microbial and/or parasitic infections in humans. 

 

A human applicable therapeutic/protective strategy against majority of serious nosocomial, community acquired and chronic microbial & parasitic illnesses is still eluding researchers. A feasible and relevant strategy for developing an effective therapeutic vaccine lies in the three important aspects; 

     

     a) identification of specific virulence determinants that are involved pathogenesis, 
     b) appreciating the cellular mechanisms involved and 
     c) determining and parsing the complex immune responses against pathogens in   
humans. 

 

During my PhD, I worked on structural vaccinology, infection and immunotherapy fields and in my time at Temple University, Philadelphia, as a postdoc, I worked on HSV-1 immunopathology and was trained in mice colony and health maintenance. Currently, at IIT Roorkee, I am involved in studying the role of small RNAs in regulating the virulence mechanisms in Acinetobacter baumannii. 

POSTDOC EXPERIENCE

JUNE 2016 TO NOV 2017 

Postdoctoral Researcher

Dept of Immunology & Microbiology

Temple University, Philadelphia, USA

Project: Role of IL-36 antibodies against HSV-1 infections in mice

April 2017 to Present

Postdoctoral Researcher

Dept of Biotechnology

IIT, ROORKEE, India

Project: Role of small RNAs in A. baumannii virulence

EDUCATION

RESEARCH INTERESTS

Structural and chimeric vaccinology

Bacterial vaccines and therapeutics

2012-2015

Bharathiar University, Coimbatore, India

PhD in Microbiology

Bacterial Small Regulatory RNAs

Hfq-sRNA mediated regulation of bacterial physiology, virulence and antibiotic resistance

Molecular diagnostics

MoAb and Real time PCR based bacterial diagnostics

DNA fingerprinting

Bacterial and fungal molecular phylogenetic analysis

2009-2012

Defence Food Research Laboratory, Mysore, India

Junior Research Fellow

2007 - 2009

Sri Sathya Sai University, Prasanthi Nilayam, India

MSc Biosciences Hons. CGPA: 5.00/5.00

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