
Siva Ramakrishna
Uppalapati
Indian Institute of Technology Roorkee
Roorkee, Uttarakhand, India
Email: meetsivaram@gmail.com
Mobile: +91 9686017224

See what others had seen...
but think what others had NOT thought.
PUBLICATIONS
“If I have seen further, it is by standing on the shoulders of giants”
- Sir Issac Newton -

Academic Publications
PhD Thesis:
Generation and Characterization of a BivalentAlpha Toxin Chimera from Clostridium perfringens and Staphylococcus aureus for Detection and Prophylactic Applications. Published in Oct, 2015. Bharathiar University, Coimbatore, India
MSc project dissertation:
Studies on Aerobiology of Prasanthi Nilayam, India. Published in March, 2009. Sri Sathya Sai University, Prasanthi Nilayam, India
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Singh K, AK Singh, SR Uppalapati, Parida M & JJ Kingston (2019). Immunogenicity and protective efficacy of Burkholderia pseudomallei BLF1-N and BLF1-C terminal domains against BLF1 toxin. International Immunopharmacology. Accepted. (IF: 3.361).
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Jayaprahash C, SR Uppalapati & JJ Kingston (2019). SYBR green real-time PCR assay for detection of the indicator Bacillus cereus to validate thermal processing of Tender Coconut Water. Journal of Pure and Applied Microbiology, 13(3). (ISSN: 2581-690X).
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Milora KA, SR Uppalapati, L.E. Jensen (2017) 632. IL-36β provides protection against herpes simplex virus-1. Journal of Investigative Dermatology, 137(5), Sup 1:S109.
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Milora KA., SR Uppalapati, Sanmiguel JC, Zou W & Jensen LE. (2017). Interleukin-36β provides protection against HSV-1 infection, but does not modulate initiation of adaptive immune responses. Scientific Reports, 7, 5799. (IF: 4.525).
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Litty Babu, SR Uppalapati, HS Murali, Prakash KR (2017) Evaluation of Recombinant Multi-Epitope Outer Membrane Protein based Klebsiella pneumoniae Subunit Vaccine in Mouse Model. Frontiers in Microbiology, 8, 1805. (IF: 4.076).
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Chitradevi STS, Kaur G, SR Uppalapati, et al., (2016) Development of recombinant vaccine candidate molecule against Shigella infection. Vaccine, 34, p.5376-5383. (IF: 3.269).
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Nirmaladevi D, M Venkataramana, SR Uppalapati, et al., (2015) Molecular phylogeny, pathogenicity and toxigenicity of Fusarium oxysporum f. sp. lycopersici. Scientific Reports 6, 21367. (IF: 4.525).
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R Rashmi, M Venkataramana, SR Uppalapati, et al., (2015) Development of sandwich dot-ELISA for specific detection of Ochratoxin A and its application on to contaminated cereal grains originating from India. Frontiers in Microbiology, 6:511. (IF: 4.076).
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Chitradevi STS, Kaur G, SR Uppalapati, et al., (2015) Co-administration of rIpaB domain of Shigella with rGroEL of S. Typhi enhances the immune responses and protective efficacy against Shigella infection. Cellular & Molecular Immunology, 12, 757. (IF: 8.213).
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Kingston, JJ, Majumder, S, SR Uppalapati, Makam, SS, et al, (2015). Anthrax outbreak among cattle and its detection by extractable antigen 1 (EA1) based sandwich ELISA and immuno PCR. Indian Journal of Microbiology, 55(1), p. 29-34. (IF: 0.988).
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Shreya D, SR Uppalapati, JJ Kingston, et al., (2015) Immunization with recombinant bivalent chimera r-Cpae confers protection against alpha toxin and enterotoxin of Clostridium perfringens type A in murine model. Molecular Immunology. 65, p.51-57. (IF: 3.064).
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SR Uppalapati, JJ Kingston, HS Murali, HV Batra (2014) Heterologous protection against alpha toxins of Clostridium perfringens and Staphylococcus aureus induced by binding domain recombinant chimeric protein. Vaccine, 32, p.3075-3081. (IF: 3.269).
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SR Uppalapati, JJ Kingston, IA Qureshi, HS Murali, HV Batra (2013) In Silico, In Vitro and In Vivo Analysis of Binding Affinity between N and C-Domains of Clostridium perfringens Alpha Toxin. PLoS ONE, 8, e82024. (IF: 2.776).
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MS Shivakiran, JJ Kingston, SR Uppalapati, et al., (2013) Application of Extractable Antigen 1 (EA1) for specific detection of Bacillus anthracis cells. International Journal of Pharma and Bio Sciences, 4(2): p.274–283. (ISSN: 2230-7605).
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SR Uppalapati, JJ Kingston, HS Murali, HV Batra (2013) Taguchi Optimization of Duplex PCR for Simultaneous Identification of Staphylococcus aureus and Clostridium perfringens Alpha Toxins. FEMS Microbiology Letters, 340, p.93-100. (IF: 1.994).
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R Rashmi, MV Ramana, R Shylaja, SR Uppalapati, et al., (2012) Evaluation of a multiplex PCR assay for concurrent detection of four major mycotoxigenic fungi from foods. Journal of Applied Microbiology, 114(3), p. 819-27. (IF: 2.683).
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SR Uppalapati, JJ Kingston, HS Murali, HV Batra (2012) Generation and Characterization of an Inter-Generic Bivalent Alpha Domain Fusion Protein αCS from Clostridium perfringens and Staphylococcus aureus for Concurrent Diagnosis and Therapeutic Applications. Journal of Applied Microbiology, 113, p.448–458. (IF: 2.683).
Patents
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A monoclonal antibody specific for rea1-c of Bacillus anthracis and a process for preparation thereof (2013). Harsh Vardhan Batra, Joseph Kingston Jeyabalaji, Shivakiran Makam Sathyanarayan, Siva Ramakrishna Uppalapati, Radhika Madan Urs, Harishchandra Sripathy Murali, Urmil Tuteja and Amarinder Singh Bawa. Indian Patent file No. 2880/DEL/2011.
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A chimeric gene r-αcs encoding fusion protein composed of alpha toxins of Clostridium perfringens and Staphylococcus aureus. Siva Ramakrishna Uppalapati, Joseph Kingston Jeyabalaji, Harishchandra Sripathy Murali, Harsh Vardhan Batra. Indian Patent file No. 726/DEL/2013.
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A chimeric gene r-cpae encoding fusion protein composed of alpha and enterotoxins of Clostridium perfringens. Shreya Das, Siva Ramakrishna Uppalapati, Joseph Kingston Jeyabalaji, Harishchandra Sripathy Murali, Harsh Vardhan Batra. Indian Patent file No. 1918/DEL/2014.